The treatment is contained in a small pipette designed for quick and easy application. You must apply the entire contents of the tube because the dosage is precisely measured based on your companion's weight. Please remain vigilant and ensure you are using a product specifically formulated for both the species and the exact weight of your animal. To achieve the best results, you should apply the solution directly to the skin.
Apply the product uniformly directly onto the skin surface at several points along your dog's back. Do not rub in the product and allow it to dry naturally.

Choosing the right flea treatment for your dog is essential to ensure your pet receives the most appropriate level of protection. Elanco offers two distinct types of canine treatments, which are Advantage II and K9 Advantix II.
While Advantage II focuses primarily on eliminating fleas and lice, K9 Advantix II provides broader protection by also targeting ticks, mosquitoes, and biting flies. If your dog frequently explores tall grass or wooded areas, K9 Advantix II is the recommended choice to prevent tick-borne threats. You can review their specific differences below to make the best decision for your pet's lifestyle.

K9 Advantix II is highly safe for dogs when used strictly according to the label instructions. As a topical treatment, it is not absorbed into the bloodstream; however, you must ensure that you follow the correct dosage based on your dog's specific weight.

• K9 Advantix II for small dogs weighing up to 4.5 kg
• K9 Advantix II for medium dogs weighing between 4.6 kg and 11 kg
• K9 Advantix II for large dogs weighing between 11 kg and 25 kg
• K9 Advantix II for extra large dogs weighing over 25 kg

This product is formulated exclusively for dogs. Due to its permethrin content, it is extremely toxic to cats. If your dog lives with a cat, you must keep them separated for approximately 24 hours until the product is completely dry to prevent your cat from licking the application site.

As with any treatment, rare side effects may occur. The most common issues include temporary redness, irritation, or itching at the specific site where the product was applied. These effects typically depend on your dog's individual sensitivity. If these symptoms persist or become more severe, particularly if you notice any changes in your pet's behavior, please contact your veterinarian immediately.

K9 Advantix II begins killing fleas within 12 hours of application. Its repellent effect against ticks and mosquitoes becomes active as soon as the product has spread across the skin and combined with your dog's natural sebum.

A single application provides comprehensive protection for 30 days. In Canada, it is highly recommended to start treating your dog as soon as the temperature reaches 4°C, which is the exact moment when ticks become active again.

The product becomes waterproof between 24 and 48 hours after application. We recommend using a mild and non-medicated shampoo to preserve the effectiveness of the protective barrier on your dog's skin.

It is important to prevent your dog from licking the product because it may cause excessive salivation or even nausea due to the bitter taste. If this occurs, we recommend rinsing your dog's mouth with water and monitoring them closely. To ensure optimal safety, we suggest following these precautions:

• Monitor your companion for at least two hours after application to allow the product to dry completely.
• Apply the treatment correctly by following the instructions and distributing the contents of the pipette across three or four points along the spine where your pet cannot reach it.
• If you have multiple pets, separate them temporarily to prevent them from licking each other.

If your dog ingests a significant amount of the product or exhibits any abnormal behavior, please contact your veterinarian immediately.

No, you must never use K9 Advantix II for dogs on a cat because it can be toxic or even fatal to them. To protect your feline's health, always ensure that you are using Advantage II for cats or another flea treatment for cats.